Ceramide Cas 100403-19-8

Ceramide Cas 100403-19-8

Ceramides are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid. Ceramides are found in high concentrations within the cell membrane of cells, since they are component lipids that make up sphingomyelin, one of the major lipids in the lipid bilayer.

Introduction

Ceramides are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid. Ceramides are found in high concentrations within the cell membrane of cells, since they are component lipids that make up sphingomyelin, one of the major lipids in the lipid bilayer.

As a bioactive lipid, ceramide has been implicated in a variety of physiological functions including apoptosis, cell growth arrest, differentiation, cell senescence, cell migration and adhesion. Roles for ceramide and its downstream metabolites have also been suggested in a number of pathological states including cancer, neurodegeneration, diabetes, microbial pathogenesis, obesity, and inflammation.


Functions and Applications


1. Ceramides may be found as ingredients of some topical skin medications used to complement treatment for skin conditions such as eczema.    

2. They are also used in cosmetic products such as some soaps, shampoos, skin creams, and sunscreens.    

3. Ceramides are being explored as a potential therapeutic in cancer.


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