Pancreatic enzymes also known as pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems. These pancreatic problems may be due to cystic fibrosis, surgical removal of the pancreas, long term pancreatitis, or pancreatic cancer among others.
Pancreatic enzymes also known as pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems. These pancreatic problems may be due to cystic fibrosis, surgical removal of the pancreas, long term pancreatitis, or pancreatic cancer among others. It is taken by mouth. Common side effects include vomiting, abdominal pain, constipation, and diarrhea. Other side effects include perianal irritation and high blood uric acid. The enzymes are from pigs. Use is believed to be safe during pregnancy. The components are digestive enzymes similar to those normally produced by the human pancreas. They help the person digest fats, starches, and proteins. Pancreatic enzymes have been used as medications since at least the 1800s. They are on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. In the United Kingdom a typical month supply costs the NHS about 11.64 pounds. In the United States a month of treatment typically costs 50 to 100 USD.
Functions and Applications
|Pancreatin Basic information|
|Synonyms:||pancrex-v;pankreon;pankrotanon;panteric;viobin;viokase;Pancreatin NB from porcine pancreas;Pancreatin NB GMP Grade from porcine pancreas|
|Mol File:||Mol File|
|Application|| Mainly used in the leather industry, enzymatic hair removal, also used in the textile printing and dyeing industry|
Used in biochemical research, clinically used as a digestive drug for digestive disorders, loss of appetite, digestive disorders caused by pancreatic diseases, and dyspepsia in diabetic patients.
|Pancreatin Chemical Properties|
|solubility||Soluble or partly soluble in water forming a slightly turbid solution; practically insoluble in ethanol (96%) and in ether .|
|Water Solubility||Soluble in water. Insoluble in alcohol and ether.|
|Stability:||Stable. Incompatible with alcohols, strong acids.|
|EPA Substance Registry System||Pancreatin(8049-47-6)|
Dec. 19, 2019
Dec. 19, 2019